Comparison of eGFR formulas (CKD-EPI and MDRD) in patients with multiple myeloma

Purpose: Modification of Diet in Renal Disease’ (MDRD) and 'Chronic Kidney Disease Epidemiology Collaboration’ (CKD-EPI) formulas are generally accepted widely utilized tools to assess renal function. In this study, we aimed investigate the power MDRD CKD-EPI formulas, which two most used measurement eGFR patients with multiple myeloma (MM).
 Materials Methods: A total 40 patients, newly diagnosis MM, were consecutively enrolled study their records analyzed terms demographic features laboratory parameters type paraproteinemia stage disease. evaluate 
 Results: The difference found between basal third-month estimated Glomerular Filtration Rate (eGFR) using (61±15.4 mL/min/1.73 m², third month 75±18.2 m²) (62±15.7 76±18.4 significant. There was no significant regarding mean values. According CKD staging, 12.5% all subjects changed 80% them moved better stage. Conclusion: tends produce higher values compared MDRD, especially when they mildly impaired Hence, prevalence disease determined lower assessed CKD-EPI. Therefore, recommend that it is important use same estimation formula for a consistent outcomes analysis.